Do you know that taking overdose of anxiety tablets cause a lot of damage to your heart and brain? Depression affects millions of individuals and is one of the most frequent mental disorders in the United States, according to the National Institute of Mental Health (NIH). For many people, significant depression can cause a substantial paralyze or limit their ability to carry out major life tasks.
The Most Common Depression Symptoms
Depression can take several forms depending on the individual. While some may show more obvious symptoms, such as weariness and depression, others may appear more irritated or aggressive. Other symptoms of depression include:
- Disinterest in activities
- Sleep pattern changes
- Appetite changes
- Feelings of guilt or hopelessness
- Insufficient energy
- Concentration issues
- Suicidal ideation
How is an overdose handled?
Emergency responders will take you to the hospital or emergency department if you overdose. While on the way, you may be given activated charcoal.
Your doctor may pump your stomach to eliminate residual medication when you arrive at the hospital or emergency department. If you’re agitated or hyperactive, they may sedate you with benzodiazepines.
If you have serotonin syndrome symptoms, they may also give you medication to block serotonin. Intravenous (IV) fluids may also be required to replace nutrients and prevent dehydration.
You may be needed to stay in the hospital for observation after your symptoms have eased.
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What are the most common and fatal doses?
TCAs
Tricyclic antidepressants (TCAs) have the highest number of fatal overdoses compared to other antidepressants.
The usual daily dose of TCA amitriptyline is 40 to 100 milligrams (mg). The average imipramine dose is between 75 and 150 mg per day. Life-threatening symptoms are frequently encountered in quantities larger than 1,000 mg, according to a 2007 assessment of US poison centre data. The lowest deadly dose of imipramine in one clinical experiment was only 200 mg.
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SSRIs
An SSRI overdose is rarely lethal when taken alone.
The average fluoxetine (Prozac) dosage is between 20 and 80 mg daily. A dose of fluoxetine as little as 520 mg has been linked to death, although someone is ingesting 8 grams of fluoxetine and recovering. Serotonin-norepinephrine reuptake inhibitors (SNRIs) are less hazardous than TCAs but more harmful than SSRIs.
The SNRI venlafaxine is often given in two or three divided dosages of 75 to 225 mg per day.
Even at greater doses, the majority of SNRI overdoses are not lethal. The majority of fatal overdoses include multiple drugs.
MAOIs
MAOIs (monoamine oxidase inhibitors) are an older antidepressant that is no longer extensively utilized. Most MAOI toxicity instances occur when excessive doses are combined with alcohol or other medications.
Death from an MAOI overdose is uncommon. However, this is likely because they are no longer commonly prescribed due to their numerous interactions.
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